Van de Ven Brace Ends The Toffees' Run at New Stadium
The Dutch defender became the first backline player to net twice in a Premier League game for Tottenham since Jan Vertonghen in March 2013.
Key points
The Spurs defender nods into the net two times in first half
The home side's defender has equalizer ruled after VAR review
Senegalese midfielder scores final goal in 89th minute
This loss is Everton's initial at Hill Dickinson Stadium
Micky van de Ven scored twice as Spurs extended their winning streak in away games in the Premier League and handed the Toffees their initial loss at Hill Dickinson Stadium.
The Toffees were undefeated in their last five matches at their recently opened stadium at Bramley-Moore Dock, having left their historic home behind after 133 years at the conclusion of the previous campaign.
But Tottenham's leader Van de Ven pounced twice from set-pieces in the opening 45 minutes to put their strong form at risk, and they were unable to mount a comeback before Pape Matar Sarr - set up by former Toffees attacker the Brazilian - nodded in a third to seal the victory.
The Everton defender believed he had levelled the scores five minutes after Van de Ven's first goal, directing a bullet header past the Spurs keeper from an set-piece.
The Portuguese striker, meanwhile, failed to convert a number of chances, while Vicario made a succession of fine saves to guarantee the London club went five matches on the road without defeat in the Premier League.
But the video assistant referee stepped in, instructing Craig Pawson to review the goal on the screen and the referee decided that Jack Grealish and the attacker were in offside positions and had interfered with the Tottenham goalkeeper.
This victory moves the manager's team into third place in the Premier League, a handful of points off north London rivals and leaders the Gunners.
Everton remain in 14th position and sit half a dozen points ahead of the drop zone.
Tottenham analysis: Van de Ven excels in duties at each end of pitch
After a drab midweek performance in the Champions League against the French side, where they mustered a mere attempts on target, the manager opted for Randal Kolo Muani up front instead of ex-Everton forward the Brazilian.
The summer signing was unable to influence the game before being replaced for the substitute after an hour on the field, but it emerged he wasn't needed in the final outcome.
Centre-back the Dutchman converted into an attacking force to be reckoned with.
Spurs' opening strike came from a cleverly executed set-piece play, with the midfielder heading the ball back across the six-yard box for an free Van de Ven to score.
And the captain - stepping up as skipper in Cristian Romero's absence - notched his next goal in added time as he rose above the England keeper to head home.
Van de Ven was equally impressive in defence, partnering effectively with his defensive colleague as the duo dealt excellently with the numerous deliveries sent their way by the opposition.
Everton analysis: Everton lacking finishing touch
The club's recent stadium had been a fortress, but it seems the freshness may have faded somewhat and fans headed to the exits after the midfielder's third for Tottenham.
The end in the team's unbeaten home run won't be a major concern for the manager, but their attacking woes will be.
The forward and Thierno Barry - the Everton's pair of recognised centre-forwards - had netted just one league goal between them before Sunday's outing.
And they were failed to add to that poor record on a damp and dreary evening on Merseyside.
The striker's form was summed up when he opted to bicycle-kick a golden opportunity from near the goal, even with having room and opportunity to reposition for a simpler attempt that would have tested Vicario.
The substitute, too, was unable to influence the game after coming on for the starter in the 65th minute.
It wasn't for a lack of opportunity. Most of the home side's attacks came through the winger and Ndiaye, who relentlessly whipped threatening crosses into the Spurs penalty area.
Upcoming fixtures for these two sides?
The Toffees: Moyes' men travel to the Stadium of Light in the top flight on early November at 20:00 GMT.
Spurs: The London club travel to Newcastle's ground on Wednesday, 29 October for their next round League Cup tie against Newcastle.